Alzheimer's Risk Screening

Alzheimer’s Risk Screening at The Longevist Clinic

Alzheimer’s disease is a progressive neurodegenerative disorder that affects memory, cognition, and daily function. While genetics play a role, lifestyle, metabolic health, inflammation, and protein misfolding (Tau and Amyloid Beta accumulation) significantly impact your risk. At The Longevist Clinic, we offer Alzheimer’s Risk Screening, combining genetic, metabolic, inflammatory, and neurodegenerative biomarkers to assess your risk and provide early intervention strategies for brain health and longevity.

What We Test:

1. Neurodegenerative Biomarkers (Detecting Early Signs of Alzheimer’s)

Tau Protein (Total Tau & Phosphorylated Tau 181 - pTau181) – Measures abnormal tau accumulation linked to neurofibrillary tangles in Alzheimer’s disease.

Amyloid Beta 42/40 Ratio (Aβ42/Aβ40) – Assesses amyloid plaque buildup, a key feature of Alzheimer’s pathology.

2. Genetic Risk Markers

Apolipoprotein E (APOE Genotyping) – Identifies genetic risk factors for late-onset Alzheimer’s.

BDNF (Brain-Derived Neurotrophic Factor) – Supports neuroplasticity and brain resilience.

3. Neuroinflammation & Brain Health

C-Reactive Protein (CRP-hs) – Measures systemic inflammation linked to cognitive decline.

Interleukin-6 (IL-6) & TNF-alpha – Detects inflammatory cytokines affecting brain aging.

Homocysteine – Elevated levels are associated with increased Alzheimer’s risk.

4. Metabolic & Vascular Markers (Impacting Brain Health & Cognition)

Fasting Insulin & HOMA-IR (Insulin Resistance Index) – Insulin resistance is a major contributor to Alzheimer’s (Type 3 Diabetes).

HbA1c & Advanced Lipid Panel (LDL-P, ApoB, Lp(a)) – Assess cardiovascular and metabolic risks affecting brain function.

5. Oxidative Stress & Mitochondrial Function

Coenzyme Q10 & NAD+ Levels – Evaluate cellular energy and mitochondrial function.

8-OHdG (DNA Damage Marker) – Measures oxidative damage linked to neurodegeneration.

6. Gut-Brain Axis & Toxin Exposure

Comprehensive Stool Test – Assesses gut microbiome imbalances affecting brain function.

Urine Heavy Metal Test (Lead, Mercury, Aluminum) – Identifies neurotoxic metals contributing to cognitive decline.

7. Cognitive Function Assessment

Neurocognitive Testing – Evaluates memory, processing speed, executive function, and attention.

Who Should Get an Alzheimer’s Risk Screening?

Individuals with a family history of Alzheimer’s or dementia

Those experiencing brain fog, memory lapses, or cognitive decline

Individuals with chronic inflammation, insulin resistance, or metabolic syndrome

Anyone seeking early intervention strategies to protect brain health and longevity

Early detection and proactive strategies can reduce cognitive decline and support lifelong brain health.

📅 Book your Alzheimer’s Risk Screening today and take a proactive approach to cognitive longevity!